1, pancreatic cancer in the early sudden weight loss: more than half of the pancreatic cancer there will be a sudden weight loss phenomenon, and some patients find finally thin down, secretly pleased be careful when pancreatic oh. Emaciated causes include cancer consumption, loss of appetite, anxiety, insomnia, digestion and absorption disorders such as pancreatic cancer early symptoms.

       2, pancreatic cancer in the early weakness and loss of appetite: some pancreatic cancer coexisting will often feel fatigue, lack of appetite, diarrhea, abdominal distension, sometimes some gastrointestinal symptoms. Don’t like fatty food, also can appear fat diarrhea, it is fat is not digested, and fecal excretion and mixed, the diarrhea symptoms.

      3, pancreatic cancer in the early abdominal pain: pancreatic cancer early symptoms may become now pancreatic body and the head of the pancreas site, located in the right upper abdomen position, sometimes appear stomach cramps or persistent pain, then beware of pancreatic cancer.

      4, pancreatic cancer in the early jaundice jaundice symptoms are: pancreatic cancer at some stage there will be symptoms of pancreatic cancer, sometimes early disease is confined to the pancreatic body, which for pancreatic cancer is relatively good treatment. Jaundice is more obstructive, progressively deepened, accompanied by itchy skin, such as tea color of urine, feces into clay color.

       In addition to loss of appetite, what ‘s the other symptom of Pancreatic cancer? You know what are the symptoms of early pancreatic cancer? This problem you know? You are there any questions? Experts explain, pancreatic cancer early symptoms in addition to these phenomena, there will be some such phenomena as heat, this time through the exclusion of pancreatic carcinoma disease to effectively restore health. Pancreatic cancer patients can pass through the body improve body immunity to struggle with the disease, out of the disease area.

       1, common pancreatic cancer symptoms were abdominal pain, jaundice. Pancreatic cancer disease often have epigastric discomfort phenomenon, some may present with abdominal pain, pancreatic carcinoma is the most common symptoms, above about 60% patients as the first symptom. Pancreatic cancer pain location of deep, not very accurate position, above the abdomen up to see. Jaundice were mainly found in the pancreatic head carcinoma cases. Some patients can jaundice as the initial symptom. Pancreatic cancer with obstructive jaundice jaundice belongs, by tumor obstruction or compression of the distal common bile duct caused by. In addition to significant jaundice, patients may also appear itchy skin, anemia and bleeding tendency. Pancreatic adenocarcinoma presenting extrahepatic obstructive jaundice, sometimes palpable and enlargement of gallbladder.
      2, common pancreatic cancer symptoms have thin, abdominal mass. Pancreatic cancer wasting is typical, and sometimes it is more sudden. Pancreatic cancer is characterized by fast development of thin. Loss of appetite, indigestion, nausea and vomiting, diarrhea and constipation alternately or constipation and other symptoms occur, but is not specific. Location of the pancreas is deep, pancreatic cancer is usually inaccessible abdominal mass. Once a palpable mass, either primary or metastatic lesions showed course late. Some patients may appear thrombophlebitis, symptomatic glycosuria and psychiatric symptoms. Approximately 50% of patients can have hepatomegaly, its reason to cholestatic, even for portal hypertension or metastasis induced by. . good, good.

        In life, which is the common symptoms of pancreatic cancer? What characteristics are obvious? Is it right? Know the answer? A scholarly introduction, these are the symptoms of pancreatic cancer, although not the same as the presenting symptoms may vary, but most patients symptoms can hardly open above introduction. For the early detection and treatment of pancreatic cancer patients, need for their symptoms to attention, but don’t let go or blind treatment.

      Pancreatic cancer incidence, and the sweets and meat intake, smoking, excessive drinking and other bad factors closely related to obesity. Hao Jihui said, when people eat, can stimulate the secretion of pancreatic digestive enzymes of pancreatic juice contains a large number of. Pancreatic juice and bile into the intestine digestive together, eating meat, oil and rice. If the intake of fat, starch, protein and other excessive, will cause excessive load on the pancreas, pancreatic cell malignant transformation occurs, induced pancreatic diseases. In addition, and never to have a drink with sugar compared to the people, two times a day to drink sugary beverages, to pancreatic cancer risk increased significantly.

     Eating too much sweet food reduces child immunity
     The child was sick, a lot of parents will let them eat cake is a kind of dessert. In fact, this is not conducive to the rehabilitation of sick children. Recent studies have shown that, sweets can reduce the human body immunity.

      Prevalence of children, the secretion of digestive juice reduced, digestive enzyme activity decreased gastrointestinal motility, slow, digestive malfunction,so often loss of appetite. Sit cross-legged if allow children to eat too many sweets, the body can consume large amounts of vitamins, human body lacks certain vitamins, oral cavity saliva, gastrointestinal digestive fluid will decrease, which will more poor appetite. Especially before meals to eat more sweets, will be caused by elevated blood sugar, more sick children will lose their hunger, to eat more reluctant to eat. TCM believes that ” Gan to injuries of the spleen”, and tells the truth.

       In general, pancreatic cancer more nausea and vomiting, abdominal pain, jaundice and gastrointestinal symptoms as primary manifestation. But this year to clinical found a pancreatic cancer first to “diabetes” appearance on stage, a few months or half a year after just appear obvious gastrointestinal symptoms.

      Why should  diabetic patients alert pancreatic cancer? There have been reports of some patients with pancreatic cancer diagnosed before two years of above history of diabetes. Pancreatic cancer with diabetes as the first manifestation, its exact mechanism is still not clear. Some people think that pancreatic cancer can be produced by a specific factor, can antagonize insulin hypoglycemic effect; some people think it is the destruction of islet cell tumor infiltration, make insulin production decline. Due to the lack of specific symptoms of early pancreatic cancer, diagnosis is difficult. Some patients with pancreatic cancer if the” diabetes” show appearances, think of a pancreatic cancer may be caused by, vigilance, then can help early diagnosis; for some elderly onset diabetes after regular treatment in poorly controlled or and the emergence of gastrointestinal symptoms, particularly persistent epigastric pain, then should be asked in detail about the history, thorough physical examination and targeted auxiliary examination. Such as B-mode ultrasonography is a simple and convenient inspection method, dynamic repeated examinations, if necessary, with CT or MRI; serological markers, such as CA50( serum sugar chains of glycogen,50) CA19-9, CEA ( carcinoembryonic antigen ) has certain value on diagnosis of.

       Pancreatic cancer on astronomical location research, such as the settlers research, fully illustrated environmental factors, such as diet carcinogenic effect. Animal experiments have proved the high fat diet and cancer of pancreas development. Other such as meat and high calorie diet, especially high in carbohydrates, dairy products and marine food and relevant factors. While the diet structure high in fiber, fruits and fresh vegetables of people suffering from pancreatic cancer is less. Although caffeine consumption of alcoholic beverages is thought to be a growing risk factor, but there are a lot of studies do not support this idea.

      Similarly, many studies do not support the relationship between diabetes and pancreatic cancer, although there are some prospective research shows people with diabetes the risk of pancreatic cancer is 4 times higher than the others. In recent years, people now pancreatic carcinoma confirmed several months often have diabetes, a finding that may prompt physicians to diabetes family history in the middle-aged patient to consider the possibility of early pancreatic cancer.

       In pancreatic cancer and the occupation is related with chemicals and metal contact, there are researchers think with benzene beta-naphthylamine and related work in factories of men at high risk of developing pancreatic cancer.

     Pancreatic cancer genetic elements have not been understood that, but there are also family morbidity report. Recent research that close relatives have malignant pancreatic tumor prevalence risk high.

 
      Prevalence of pancreatic cancer usually around the age of 60, and in males than in females. Interventional therapy is the recent emergence of treatment approaches, experts interventional therapy of pancreatic carcinoma has the characteristics of safe, minimally invasive, high efficiency, less complication, less toxic side effect and other advantages, is one of the best ways in treatment of pancreatic cancer. Both bear such treatment approaches, to choose suitable treatment options, select the minimal damage, the effect of the best therapeutic approach.

        Upper abdominal pain and abdominal distention abdominal pain is a common symptom in patients with carcinoma of the pancreatic head carcinoma of body and tail of pancreas, and the most prominent symptoms. Abdominal pain and on the location of the tumor. Pancreatic head carcinoma, pancreatic carcinoma of body and tail of pancreas carcinoma and abdominal pain occurring at a rate of 83.7%. Pancreatic cancer pain has varied, in the course of the disease can also be changed, this is because the lesion site and cause abdominal pain is not consistent. Abdominal pain in epigastric middle part, but the pancreatic head cancer pain can be skewed to the right upper quadrant, carcinoma of body and tail can be to the left upper quadrant abdominal pain, sometimes also can be in the navel or whole abdomen. Abdominal pain can be roughly divided into three types:

       Of severe upper abdominal pain, may radiate to the scapular, such as biliary colic, may be due to drinking or greasy food induced, more common in pancreatic head cancer early, is possible in cases of obstruction of biliary, pancreatic duct strong contraction induced by.

      Dull pain, most, occupy about 70%, persistent or intermittent pain, often after1-2 hours after the increase, after a few hours to reduce or alleviate. If do not eat or eat less, pain tolerance, and patients often automatically restricted food intake. The pain may be caused by pancreatic duct obstruction, biliary and pancreatic duct pressure caused by increased.

      Back of upper abdominal pain,1 /4 of the patients have the symptoms. Low back pain is more significant than upper abdominal pain, pain related to both sides to help department such as bundle ribbon season, sitting, bending, side, knee flexion can be lightened, lie flat can be increased obviously, during the night than during the day. This may be due to tumor invasion, oppression caused by retroperitoneal visceral nerve, common in late pancreatic cancer, especially seen in the carcinoma of body and tail of pancreas. Clinical go up to often think this is the typical symptoms of pancreatic cancer, and was in fact a late manifestation of pancreatic cancer. Upper abdominal discomfort for epigastric plugging sensation, after the food satiety, restrict food intake and exhaust can alleviate.

    Several problems of operation in treatment of pancreatic cancer

     Pancreatic cancer during operation period treatment is to improve the cure rate, decrease the complications are important measures, for the following reasons:
     1, pancreatic carcinoma operation treatment is surgical abdominal complicated operation, long time, trauma, bleeding, many complications, high mortality.
     2, anemia, weight loss, malnutrition, should actively support therapy, aggressive correction of acid-base balance, correction of hypovolemia, hypoalbuminemia.
     3, actively correction of heart, liver, renal dysfunction, infection control, reduce operation and postoperative complications.
    4, about jaundice treatment are currently in dispute, but as a risk factor for them before the operation is considered to improve.
     Pancreatic carcinoma operation treatment principles and methods:
     Operation choice of general principles are: diagnosis and metastasis should avoid radical operation; without metastasis symptoms should be done by laparotomy and resection for biliary obstruction; and those with metastasis to bypass operation or catheter drainage. Dedecms.com
In 1, radical operation of carcinoma of head of pancreas: do pancreaticoduodenectomy or pylorus preserving pancreaticoduodenectomy as type T, resection of the pancreatic head, Department of pancreatic hook sinus, gastric antrum, duodenum, jejunum, all upper segment of common bile duct and the local lymph node, conditions should be extended resection of pancreatic body and tail; cancer, line pancreatectomy and splenectomy.
In 2, palliative operation: used in gallbladder jejunum anastomosis, percutaneous biliary drainage, or bile duct jejunum and gastro-jejunal anastomosis, or gall bladder incision.

 
     Top experts talk of pancreatic cancer operation treatment on several key issues, including why choose operation therapy treatment and operation principle.

     Advanced pancreatic cancer treatment methods mainly include: operation, radiotherapy, chemotherapy and other. The surgical operation is the first choice,  but the disease early diagnosis difficult, operation resection rate is low, only about 10% of the patients can use the operation approach for resection of tumors. Operation it still has a lot of problems: trauma, bleeding, risk of anesthesia, operation complications, infection, prolonged hospitalization, and pancreatic tissue around the complex structure, difficult operation, approximately 90% of the patients the tumor could not be resected.

      Radiation therapy for advanced pancreatic cancer patients are difficult to implement, mainly because: pancreatic cancer is radiation sensitive tissue, whereas pancreatic surrounding normal tissues such as the stomach, duodenum and radiation sensitive tissue, to give a pancreatic tumor high-dose irradiation of surrounding normal tissue, pancreas may damage. Chemotherapy for advanced pancreatic cancer action is also limited,5-Fu is the standard monotherapy, efficiency of less than 20%.

   The three conventional therapy of pancreatic cancer:

     One, surgical treatment
     The preferred method of treatment for pancreatic carcinoma operation excision, but because most cannot be found early and resection rate is low, the resection rate of about 5% ~ 15%, it is reported following curative resection of pancreatic cancer5 years survival rate of 2.3% ~ 15.8%, average3.4%, domestic reports average survival time was 17.6months after radical mastectomy. Surgical treatment of basic principles of tumor resection, reconstruction of the biliary tract, intestinal and pancreatic stump. Operation of carcinoma of head of pancreas resection rate was 30%, and the body of the pancreas tail cancer resection rate, in 5% the left and right sides.

     Radical operation for pancreatic cancer with certain contraindications: poor general condition of patients, such as high frail with multiple organ diseases; II upon physical examination, inspection or operation was confirmed to have distant metastasis; and accompanied by other serious diseases, estimated life span of patients; the surgeon inexperience or equipment operation condition of incomplete.
Pancreatic cancer resection type more debate, mainly traditional pancreaticoduodenectomy ( Whipple ), pylorus-preserving pancreatoduodenectomy ( PPPD ), total resection of the pancreas with partial pancreatectomy, extended resection of pancreatic head carcinoma resection and pancreatic body and tail carcinoma radical resection, palliative operation, and whether portal vein resection operation ( PVR ). These patients may have intraoperative, postoperative bleeding, cardiac and pulmonary complications, vascular thrombosis, infection, renal failure, pancreatic fistula, gastric retention and jaundice, diabetes, gastric jejunum anastomotic ulcer complications.

     Two, chemotherapy
    Chemotherapy is an important part of the comprehensive treatment of pancreatic cancer, is the effective means of adjuvant therapy of pancreatic cancer to chemotherapy, but the response is low, many drugs have recently efficiency is lower than 10%, more effective drugs commonly used drug, mitomycin5-FU, epirubicin, carboplatin, etc.. Gemcitabine due to its toxicity is low, small side effect, has become in recent years abroad in treatment of pancreatic cancer first-line drugs, domestic has also started to use. The results show that, receiving gemcitabine in the treatment of life quality is superior to that of 5-FU, treatment response rates and survival time is similar, but the effect is not ideal.

    Three, radiotherapy
    Pancreatic cancer  is radiotherapy was not sensitive to the tumor, but due to the limitations of advanced cases accounted for about 40%, for local radiotherapy, after treatment30% ~ 50% can relieve the pain, but the degree of inhibition of tumor development. Radiation therapy can improve the patient’s clinical symptoms, especially abdominal and back pain, but to extend advanced pancreatic cancer patient survival time limited.

      At present, many advocated radiotherapy, chemotherapy and operation joint application, to improve the therapeutic efficacy of. Chemotherapy drugs such as5-FU, gemcitabine and targeting agents echo Xin possess radiosensitizing effects, whereas radiotherapy due to changes in blood pancreatic barrier to chemotherapeutic drug permeability, in turn, may increase the effects of chemotherapy and Ke xin. Conformal radiotherapy, intensity-modulated radiotherapy, especially in recent years, radiotherapy is one of the important progress.

   In this situation,how to treat early pancreatic cancer patients?

      First of all, should be based on the patient’s own body and tumor development level of comprehensive consideration.

      If the suitable operation excision, can according to the patient’s tumor site, size, development degree take a partial resection or pancreatic resection. Pancreatic cancer in patients with early operation resection including pancreas duodenum resection, pylorus-preserving pancreatoduodenectomy, combined with vascular resection of pancreatic cancer operation, body and tail of pancreas resection, total pancreatic resection. Unresectable pancreatic cancer operation therapy include biliary drainage, gastro-jejunostomy, biliary obstruction, such as gastrointestinal anastomosis.

        Pancreatic cancer in patients with early operation resection combined with chemotherapy after the needs of patients to control symptoms, prevent metastatic spread. Also need to note is, early pancreatic cancer patients undergoing operation after treatment will feel very tired, need timely take Chinese traditional medicine to improve the patient’s own resistance.

      Neither operation is not suitable for chemotherapy patients, either in pancreatic cancer treatment early or late treatment were only used in traditional Chinese medicine to help patients improve their own resistance, and to effectively inhibit cancer cells, to control the patient’s symptoms, for patients with stable condition.

       To sum up, the early pancreatic cancer patients in the treatment of patients with certain according to oneself circumstance and the detailed condition of patients with appropriate treatment method. Appeared at present the difficulty lies not in pancreatic cancer in the early treatment of early pancreatic cancer, but it is easy to neglect for patients, leading to treatment too late, so we must prompt vigilance pancreatic cancer early symptoms.